Suppression of Melanoma Cell Proliferation by Histidine Decarboxylase Specific Antisense Oligonucleotides
نویسندگان
چکیده
منابع مشابه
Efficient stimulation of site-specific ribosome frameshifting by antisense oligonucleotides.
Evidence is presented that morpholino, 2'-O-methyl, phosphorothioate, and RNA antisense oligonucleotides can direct site-specific -1 translational frameshifting when annealed to mRNA downstream from sequences where the P- and A-site tRNAs are both capable of repairing with -1 frame codons. The efficiency of ribosomes shifting into the new frame can be as high as 40%, determined by the sequence ...
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Marvin Rubenstein1,2,3,4*, Courtney MP Hollowell2 and Patrick Guinan1,2,4,5 1Division of Cellular Biology, Hektoen Institute for Medical Research 2Division of Urology, Stroger Hospital of Cook County Departments of 3Biochemistry and 4Urology, Rush University Medical Center 5Department of Urology, University of Illinois at Chicago, Chicago, IL, 60612 Cancer Science & Research: Open Access Open A...
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We have used antisense phosphorothioate oligonucleotides to define the role played by proliferating cell nuclear antigen (PCNA) in neointimal accumulation of smooth muscle cells in a rat carotid artery injury model. The short-term extraluminal delivery of 250 nmol of antisense oligonucleotides, but not control oligonucleotides, immediately after arterial injury produces a 77% suppression of PCN...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2001
ISSN: 0022-202X
DOI: 10.1046/j.0022-202x.2001.01406.x